The benefits of 7-keto-DHEA supplementation are not definitively established. The health claims on potential weight loss benefits are not supported by solid evidence. The current evidence is mixed and limited by factors such as small sample sizes, short study durations, and a lack of diversity in the study populations. The safety profile of 7-keto-DHEA appears to be generally well-tolerated with a low side-effect profile, but changes in blood hormone parameters have been reported. Given these uncertainties, the potential benefits and safety of 7-keto-DHEA, particularly with long-term use, are not established. The US Food and Drug Administration (FDA) has not added 7-keto-DHEA to the list of bulk drug substances due to a lack of clinical evidence regarding its safety and efficacy. 7-keto-DHEA when dieting due to increased metabolic rate. Still, these claimed benefits are not supported by solid evidence. 7-Keto-DHEA has also been marketed by alternative medicine providers as a treatment of adrenal fatigue, a pseudo-scientific term with no scholarly basis. Look into my web blog - https://teslawiki.cz/index.php/User:Sabine83O8